A spokesperson for the agency reiterated the position in an email to JAMA in September. No, says the US Food and Drug Administration (FDA), which discouraged antibody testing as a do-it-yourself immunity check in a communication to the public and clinicians this past spring. Could a simple blood test reveal whether the vaccine was working or, later, if it was time for a booster shot? But for some, the arrival of COVID-19 vaccines revived their interest in serology. Which specific antibodies guarded against SARS-CoV-2 reinfection? How high did their levels need to be? And how long would they provide a reliable defense?Īs the assays’ usefulness for individual patients became less clear and testing for active infections expanded, the public’s clamor for antibody testing waned. More fundamentally, the so-called correlates of protection were unknown. The early consumer tests’ accuracy was unproven, making the results somewhat dubious.
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